Electrophysiological biomarkers in spinal muscular atrophy: proof of concept

OBJECTIVE: Preclinical therapies that restore survival motor neuron (SMN) protein levels can dramatically extend survival in spinal muscular atrophy (SMA) mouse models. Biomarkers are needed to effectively translate these promising therapies to clinical trials. Our objective was to investigate elect...

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Detalles Bibliográficos
Main Authors: David Arnold, W, Porensky, Paul N, McGovern, Vicki L, Iyer, Chitra C, Duque, Sandra, Li, Xiaobai, Meyer, Kathrin, Schmelzer, Leah, Kaspar, Brian K, Kolb, Stephen J, Kissel, John T, Burghes, Arthur H M
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914317/
https://ncbi.nlm.nih.gov/pubmed/24511555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.23
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