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Antisense oligonucleotides and spinal muscular atrophy: skipping along

Antisense oligonucleotides (ASOs) can be used to alter the splicing of a gene and either restore production of a required protein or eliminate a toxic product. In this issue of Genes & Development, Hua and colleagues (pp. 1634–1644) show that ASOs directed against an intron splice silencer (ISS)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Burghes, Arthur H.M., McGovern, Vicki L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912553/
https://ncbi.nlm.nih.gov/pubmed/20679391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1961710
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