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Antisense oligonucleotides and spinal muscular atrophy: skipping along
Antisense oligonucleotides (ASOs) can be used to alter the splicing of a gene and either restore production of a required protein or eliminate a toxic product. In this issue of Genes & Development, Hua and colleagues (pp. 1634–1644) show that ASOs directed against an intron splice silencer (ISS)...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912553/ https://ncbi.nlm.nih.gov/pubmed/20679391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1961710 |
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