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A two-domain elevator mechanism for sodium/proton antiport
Sodium/proton (Na(+)/H(+)) antiporters, located at the plasma membrane in every cell, are vital for cell homeostasis(1). In humans, their dysfunction has been linked to diseases, such as, hypertension, heart failure and epilepsy and they are well-established drug targets(2). The best understood mode...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914025/ https://ncbi.nlm.nih.gov/pubmed/23995679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12484 |
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