Escherichia coli Deletion Mutants Illuminate Trade-Offs between Growth Rate and Flux through a Foreign Anabolic Pathway

Metabolic engineers strive to improve the production yields of microbial fermentations, sometimes by mutating the genomes of production strains. Some mutations are detrimental to the health of the organism, so a quantitative and mechanistic understanding of the trade-offs could inform better designs...

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Detaylı Bibliyografya
Asıl Yazarlar: Falls, Kelly C., Williams, Aimee L., Bryksin, Anton V., Matsumura, Ichiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913754/
https://ncbi.nlm.nih.gov/pubmed/24505410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088159
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