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Multiplex genetic cancer testing identifies pathogenic mutations in TP53 and CDH1 in a patient with bilateral breast and endometrial adenocarcinoma

BACKGROUND: Germline genetic testing for familial cancer syndromes is usually performed serially for the most likely genetic causes. In recent years the way genetic testing carried out has changed, as next generation sequencing now allows the simultaneous testing of multiple susceptibility genes at...

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書誌詳細
主要な著者: Heitzer, Ellen, Lax, Sigurd, Lafer, Ingrid, Müller, Stephanie M, Pristauz, Gunda, Ulz, Peter, Jahn, Stephan, Högenauer, Christoph, Petru, Edgar, Speicher, Michael R, Geigl, Jochen B
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913615/
https://ncbi.nlm.nih.gov/pubmed/24373500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-14-129
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