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Molecular Alterations of PI3K/Akt/mTOR Pathway: A Therapeutic Target in Endometrial Cancer

It is well established that the PI3K/Akt/mTOR pathway plays a central role in cell growth and proliferation. It has also been suggested that its deregulation is associated with cancer. Genetic alterations, involving components of this pathway, are often encountered in endometrial cancers. Understand...

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Detalhes bibliográficos
Main Authors: Pavlidou, Athanasia, Vlahos, Nikos F.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913524/
https://ncbi.nlm.nih.gov/pubmed/24526917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/709736
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