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Molecular Alterations of PI3K/Akt/mTOR Pathway: A Therapeutic Target in Endometrial Cancer

It is well established that the PI3K/Akt/mTOR pathway plays a central role in cell growth and proliferation. It has also been suggested that its deregulation is associated with cancer. Genetic alterations, involving components of this pathway, are often encountered in endometrial cancers. Understand...

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Autors principals: Pavlidou, Athanasia, Vlahos, Nikos F.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913524/
https://ncbi.nlm.nih.gov/pubmed/24526917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/709736
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