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Fetal Globin Gene Inducers: Novel Agents & New Potential

Inducing expression of endogenous fetal globin (γ-globin) gene expression to 60-70% of alpha globin synthesis produces β-thalassemia trait globin synthetic ratios and can reduce anemia to a mild level. Several classes of therapeutics have induced γ-globin expression in beta thalassemia patients and...

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Detalhes bibliográficos
Main Authors: Perrine, Susan P., Castaneda, Serguei A., Chui, David H., Faller, Douglas V., Berenson, Ronald J., Fucharoen, Suthat
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913055/
https://ncbi.nlm.nih.gov/pubmed/20712788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2010.05593.x
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