Rare coincident NPM1 and RUNX1 mutations in intermediate risk acute myeloid leukemia display similar patterns to single mutated cases

Eitemau Tebyg

• Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia
  gan: Alpermann, Tamara, et al.
  Cyhoeddwyd: (2016)
• Expression of CEBPA is reduced in RUNX1-mutated acute myeloid leukemia
  gan: Grossmann, V, et al.
  Cyhoeddwyd: (2012)
• Prognostic relevance of RUNX1 mutations in T-cell acute lymphoblastic leukemia
  gan: Grossmann, Vera, et al.
  Cyhoeddwyd: (2011)
• NPM1 mutated AML can relapse with wild-type NPM1: persistent clonal hematopoiesis can drive relapse
  gan: Höllein, Alexander, et al.
  Cyhoeddwyd: (2018)
• Reply to “Rare coincident NPM1 and RUNX1 mutations in intermediate risk acute myeloid leukemia display similar patterns to single mutated cases”. Haematologica 2014;99(2):e20–21.
  gan: Mendler, Jason H., et al.
  Cyhoeddwyd: (2014)