Molecular subtypes of NPM1 mutations have different clinical profiles, specific patterns of accompanying molecular mutations and varying outcomes in intermediate risk acute myeloid leukemia

Samankaltaisia teoksia

• Refractory anemia with ring sideroblasts and marked thrombocytosis cases harbor mutations in SF3B1 or other spliceosome genes accompanied by JAK2V617F and ASXL1 mutations
  Tekijä: Jeromin, Sabine, et al.
  Julkaistu: (2015)
• Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia
  Tekijä: Meggendorfer, Manja, et al.
  Julkaistu: (2014)
• NPM1 mutated AML can relapse with wild-type NPM1: persistent clonal hematopoiesis can drive relapse
  Tekijä: Höllein, Alexander, et al.
  Julkaistu: (2018)
• Rare coincident NPM1 and RUNX1 mutations in intermediate risk acute myeloid leukemia display similar patterns to single mutated cases
  Tekijä: Fasan, Annette, et al.
  Julkaistu: (2014)
• Molecular analysis of myelodysplastic syndrome with isolated deletion of the long arm of chromosome 5 reveals a specific spectrum of molecular mutations with prognostic impact: a study on 123 patients and 27 genes
  Tekijä: Meggendorfer, Manja, et al.
  Julkaistu: (2017)