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Acquired ASXL1 mutations are common in patients with inherited GATA2 mutations and correlate with myeloid transformation
Inherited or sporadic heterozygous mutations in the transcription factor GATA2 lead to a clinical syndrome characterized by non-tuberculous mycobacterial and other opportunistic infections, a severe deficiency in monocytes, B cells and natural killer cells, and progression from a hypocellular myelod...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Ferrata Storti Foundation
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3912957/ https://ncbi.nlm.nih.gov/pubmed/24077845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.090217 |
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