Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

Acquisition of additional genetic and/or epigenetic abnormalities other than the BCR/ABL fusion gene is believed to cause disease progression in chronic myeloid leukemia (CML) from chronic phase to blast crisis (BC). To gain insights into the underlying mechanisms of progression to BC, we screened D...

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Detalhes bibliográficos
Main Authors: Zhang, Su-Jiang, Ma, Li-Yuan, Huang, Qiu-Hua, Li, Guo, Gu, Bai-Wei, Gao, Xiao-Dong, Shi, Jing-Yi, Wang, Yue-Ying, Gao, Li, Cai, Xun, Ren, Rui-Bao, Zhu, Jiang, Chen, Zhu, Chen, Sai-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538883/
https://ncbi.nlm.nih.gov/pubmed/18250304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711824105
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