Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

Acquisition of additional genetic and/or epigenetic abnormalities other than the BCR/ABL fusion gene is believed to cause disease progression in chronic myeloid leukemia (CML) from chronic phase to blast crisis (BC). To gain insights into the underlying mechanisms of progression to BC, we screened D...

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Dades bibliogràfiques
Autors principals: Zhang, Su-Jiang, Ma, Li-Yuan, Huang, Qiu-Hua, Li, Guo, Gu, Bai-Wei, Gao, Xiao-Dong, Shi, Jing-Yi, Wang, Yue-Ying, Gao, Li, Cai, Xun, Ren, Rui-Bao, Zhu, Jiang, Chen, Zhu, Chen, Sai-Juan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538883/
https://ncbi.nlm.nih.gov/pubmed/18250304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711824105
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