Polymorphism of the complement receptor 1 gene correlates with the hematologic response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

Complement blockade by eculizumab is clinically effective in hemolytic paroxysmal nocturnal hemoglobinuria. However, the response is variable and some patients remain dependent on red blood cell transfusions. In 72 patients with hemolytic paroxysmal nocturnal hemoglobinuria on eculizumab we tested t...

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Xehetasun bibliografikoak
Egile Nagusiak: Rondelli, Tommaso, Risitano, Antonio M., de Latour, Régis Peffault, Sica, Michela, Peruzzi, Benedetta, Ricci, Patrizia, Barcellini, Wilma, Iori, Anna Paola, Boschetti, Carla, Valle, Veronica, Frémeaux-Bacchi, Veronique, De Angioletti, Maria, Socie, Gerard, Luzzatto, Lucio, Notaro, Rosario
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Ferrata Storti Foundation 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912955/
https://ncbi.nlm.nih.gov/pubmed/24038027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.090001
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