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Quantitative in vivo receptor binding III: Tracer kinetic modeling of muscarinic cholinergic receptor binding.

A tracer kinetic method is developed for the in vivo estimation of high-affinity radioligand binding to central nervous system receptors. Ligand is considered to exist in three brain pools corresponding to free, nonspecifically bound, and specifically bound tracer. These environments, in addition to...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Frey, K A, Hichwa, R D, Ehrenkaufer, R L, Agranoff, B W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3876561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6711
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