Quantitative in vivo receptor binding III: Tracer kinetic modeling of muscarinic cholinergic receptor binding.

A tracer kinetic method is developed for the in vivo estimation of high-affinity radioligand binding to central nervous system receptors. Ligand is considered to exist in three brain pools corresponding to free, nonspecifically bound, and specifically bound tracer. These environments, in addition to...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Frey, K A, Hichwa, R D, Ehrenkaufer, R L, Agranoff, B W
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1985
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3876561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6711
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