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Quantitative in vivo receptor binding III: Tracer kinetic modeling of muscarinic cholinergic receptor binding.

A tracer kinetic method is developed for the in vivo estimation of high-affinity radioligand binding to central nervous system receptors. Ligand is considered to exist in three brain pools corresponding to free, nonspecifically bound, and specifically bound tracer. These environments, in addition to...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Frey, K A, Hichwa, R D, Ehrenkaufer, R L, Agranoff, B W
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1985
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3876561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6711
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