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Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral blood lymphocytes and antibodies to the adducts in serum from coke oven workers.

Coke oven workers are exposed to high levels of carcinogenic polycyclic aromatic hydrocarbons, including benzo[a]pyrene (B[a]P), and are at increased risk of lung cancer. Since B[a]P is enzymatically activated to 7 beta,8 alpha-dihydroxy(9 alpha, 10 alpha)epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (B[a...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Harris, C C, Vahakangas, K, Newman, M J, Trivers, G E, Shamsuddin, A, Sinopoli, N, Mann, D L, Wright, W E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2413443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6672
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