One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells.
We have developed a host cell reactivation assay of DNA repair utilizing UV-treated plasmid vectors. The assay primarily reflects cellular repair of transcriptional activity of damaged DNA measured indirectly as enzyme activity of the transfected genes. We studied three plasmids (pSV2cat, 5020 base...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1985
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6622 |
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