One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells.
We have developed a host cell reactivation assay of DNA repair utilizing UV-treated plasmid vectors. The assay primarily reflects cellular repair of transcriptional activity of damaged DNA measured indirectly as enzyme activity of the transfected genes. We studied three plasmids (pSV2cat, 5020 base...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1985
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6622 |
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