One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells.
We have developed a host cell reactivation assay of DNA repair utilizing UV-treated plasmid vectors. The assay primarily reflects cellular repair of transcriptional activity of damaged DNA measured indirectly as enzyme activity of the transfected genes. We studied three plasmids (pSV2cat, 5020 base...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1985
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2995975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.19.6622 |
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