Enhanced passive pulmonary targeting and retention of PEGylated rigid microparticles in rats

The current study examines the passive pulmonary targeting efficacy and retention of 6 μm polystyrene (PS) microparticles (MPs) covalently modified with different surface groups [amine (A-), carboxyl (C-) and sulfate (S-)] or single (PEG(1)-) and double (PEG(2)-) layers of α,ω-diamino poly(ethylene...

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Autores principales: Kutscher, Hilliard L., Chao, Piyun, Deshmukh, Manjeet, Rajan, Sujata Sundara, Singh, Yashveer, Hu, Peidi, Joseph, Laurie B., Stein, Stanley, Laskin, Debra L., Sinko, Patrick J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912554/
https://ncbi.nlm.nih.gov/pubmed/20883756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.09.020
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