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Dissociation of Hyperglycemia from Altered Vascular Contraction and Relaxation Mechanisms in Caveolin-1 Null Mice

Hyperglycemia and endothelial dysfunction are associated with hypertension, but the specific causality and genetic underpinning are unclear. Caveolin-1 (cav-1) is a plasmalemmal anchoring protein and modulator of vascular function and glucose homeostasis. Cav-1 gene variants are associated with redu...

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Détails bibliographiques
Auteurs principaux: Pojoga, Luminita H., Yao, Tham M., Opsasnick, Lauren A., Garza, Amanda E., Reslan, Ossama M., Adler, Gail K., Williams, Gordon H., Khalil, Raouf A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912545/
https://ncbi.nlm.nih.gov/pubmed/24281385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.209189
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