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Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice
OBJECTIVE: To test the hypothesis that aliskiren improves the metabolic phenotype in a genetic mouse model of the metabolic syndrome (the caveolin-1 knock out (KO) mouse). MATERIALS/METHODS: Eleven-week-old cav-1 KO and genetically matched wild-type (WT) mice were randomized to three treatment group...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518593/ https://ncbi.nlm.nih.gov/pubmed/22954672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2012.07.013 |
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