Direct renin inhibition modulates insulin resistance in caveolin-1-deficient mice

OBJECTIVE: To test the hypothesis that aliskiren improves the metabolic phenotype in a genetic mouse model of the metabolic syndrome (the caveolin-1 knock out (KO) mouse). MATERIALS/METHODS: Eleven-week-old cav-1 KO and genetically matched wild-type (WT) mice were randomized to three treatment group...

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Huvudupphovsmän: Chuengsamarn, Somlak, Garza, Amanda E., Krug, Alexander W., Romero, Jose R., Adler, Gail K., Williams, Gordon H., Pojoga, Luminita H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518593/
https://ncbi.nlm.nih.gov/pubmed/22954672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2012.07.013
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