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Amplification and thrifty single-molecule sequencing of recurrent somatic structural variations

Deletion of tumor-suppressor genes as well as other genomic rearrangements pervade cancer genomes across numerous types of solid tumor and hematologic malignancies. However, even for a specific rearrangement, the breakpoints may vary between individuals, such as the recurrent CDKN2A deletion. Charac...

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Detalhes bibliográficos
Main Authors: Patel, Anand, Schwab, Richard, Liu, Yu-Tsueng, Bafna, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912422/
https://ncbi.nlm.nih.gov/pubmed/24307551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161497.113
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