A Comparison of Single Molecule and Amplification Based Sequencing of Cancer Transcriptomes

The second wave of next generation sequencing technologies, referred to as single-molecule sequencing (SMS), carries the promise of profiling samples directly without employing polymerase chain reaction steps used by amplification-based sequencing (AS) methods. To examine the merits of both technolo...

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Detalhes bibliográficos
Main Authors: Sam, Lee T., Lipson, Doron, Raz, Tal, Cao, Xuhong, Thompson, John, Milos, Patrice M., Robinson, Dan, Chinnaiyan, Arul M., Kumar-Sinha, Chandan, Maher, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046973/
https://ncbi.nlm.nih.gov/pubmed/21390249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017305
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