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Effects of tissue plasminogen activator and annexin A2 combination therapy on long-term neurological outcomes of rat focal embolic stroke

BACKGROUND AND PURPOSE: Tissue type plasminogen activator (tPA) in combination with recombinant annexin A2 (rA2) is known to reduce acute brain damage after focal ischemia. Here, we ask whether tPA plus rA2 combination therapy can lead to sustained long term neurological improvements as well. METHOD...

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Библиографические подробности
Главные авторы: Wang, Xiaoshu, Fan, Xiang, Yu, Zhanyang, Liao, Zhengbu, Zhao, Jianhua, Mandeville, Emiri, Guo, Shuzhen, Lo, Eng H., Wang, Xiaoying
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912312/
https://ncbi.nlm.nih.gov/pubmed/24368559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.003823
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