15-PGDH inhibits hepatocellular carcinoma growth through 15-keto-PGE(2)/PPARγ-mediated activation of p21(WAF1/Cip1)

15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a key enzyme in prostaglandin metabolism. This study provides important evidence for inhibition of hepatocellular carcinoma (HCC) growth by 15-PGDH through the 15-keto-PGE(2)/PPARγ/p21(WAF1/Cip1) signaling pathway. Forced overexpression of 15-PGDH i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lu, Dongdong, Han, Chang, Wu, Tong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912217/
https://ncbi.nlm.nih.gov/pubmed/23542179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.69
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky