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Targeted p21(WAF1/CIP1) Activation by RNAa Inhibits Hepatocellular Carcinoma Cells

RNA activation (RNAa) is a mechanism of gene activation triggered by promoter-targeted small double-stranded RNA (dsRNA), also known as small activating RNA (saRNA). p21(WAF1/CIP1) (p21) is a putative tumor suppressor gene due to its role as a key negative regulator of the cell cycle and cell prolif...

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Bibliographic Details
Main Authors: Kosaka, Mika, Kang, Moo Rim, Yang, Glen, Li, Long-Cheng
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464408/
https://ncbi.nlm.nih.gov/pubmed/22909100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2012.0354
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