Controllability Analysis of Protein Glycosylation in Cho Cells

To function as intended in vivo, a majority of biopharmaceuticals require specific glycan distributions. However, achieving a precise glycan distribution during manufacturing can be challenging because glycosylation is a non-template driven cellular process, with the potential for significant uncont...

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Autori principali: St. Amand, Melissa M., Tran, Kevin, Radhakrishnan, Devesh, Robinson, Anne S., Ogunnaike, Babatunde A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912168/
https://ncbi.nlm.nih.gov/pubmed/24498415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087973
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