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The Molecular Defect in a Protein (CRA) Found in γ1 Heavy Chain Disease, and Its Genetic Implications
A γ1 protein, designated CRA, found in heavy chain disease contains three inter-heavy disulfide bridges instead of the two normally found in γ1 immunoglobulin heavy chains. Almost the entire Fd fragment is missing. The NH(2) terminal region is heterogeneous and contains carbohydrate; after 11 residu...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1971
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC391192/ https://ncbi.nlm.nih.gov/pubmed/4100047 |
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