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The Molecular Defect in a Protein (CRA) Found in γ1 Heavy Chain Disease, and Its Genetic Implications

A γ1 protein, designated CRA, found in heavy chain disease contains three inter-heavy disulfide bridges instead of the two normally found in γ1 immunoglobulin heavy chains. Almost the entire Fd fragment is missing. The NH(2) terminal region is heterogeneous and contains carbohydrate; after 11 residu...

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Detalhes bibliográficos
Main Authors: Franklin, E. C., Frangione, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC391192/
https://ncbi.nlm.nih.gov/pubmed/4100047
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