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Following Gene Duplication, Paralog Interference Constrains Transcriptional Circuit Evolution

Most models of gene duplication assume that the ancestral functions of the preduplication gene are independent and can therefore be neatly partitioned between descendant paralogs. However, many gene products, such as transcriptional regulators, are components within cooperative assemblies; here, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Baker, Christopher R., Hanson-Smith, Victor, Johnson, Alexander D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911913/
https://ncbi.nlm.nih.gov/pubmed/24092741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240810
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