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Synthetic circuits reveal how mechanisms of gene regulatory networks constrain evolution

Phenotypic variation is the raw material of adaptive Darwinian evolution. The phenotypic variation found in organismal development is biased towards certain phenotypes, but the molecular mechanisms behind such biases are still poorly understood. Gene regulatory networks have been proposed as one cau...

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Bibliografiske detaljer
Udgivet i:Mol Syst Biol
Main Authors: Schaerli, Yolanda, Jiménez, Alba, Duarte, José M, Mihajlovic, Ljiljana, Renggli, Julien, Isalan, Mark, Sharpe, James, Wagner, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6129954/
https://ncbi.nlm.nih.gov/pubmed/30201776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20178102
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