Differential Accessibility of a Rotavirus VP6 Epitope in Trimers Comprising Type I, II, or III Channels as Revealed by Binding of a Human Rotavirus VP6-Specific Antibody

Previous human antibody studies have shown that the human V(H)1–46 antibody variable gene segment encodes much of the naturally occurring human B cell response to rotavirus and is directed to virus protein 6 (VP6). It is currently unknown why some of the V(H)1-46-encoded human VP6 monoclonal antibod...

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Hlavní autoři: Aiyegbo, Mohammed S., Eli, Ilyas M., Spiller, Benjamin W., Williams, Dewight R., Kim, Robert, Lee, David E., Liu, Tong, Li, Sheng, Stewart, Phoebe L., Crowe, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911710/
https://ncbi.nlm.nih.gov/pubmed/24155406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01665-13
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