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The Human Alpha Defensin HD5 Neutralizes JC Polyomavirus Infection by Reducing Endoplasmic Reticulum Traffic and Stabilizing the Viral Capsid

Progressive multifocal leukoencephalopathy (PML) is a fatal disease with limited treatment options, both clinically and in the research pipeline. Potential therapies would target and neutralize its etiologic agent, JC polyomavirus (JCPyV). The innate immune response to JCPyV infection has not been s...

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書誌詳細
主要な著者: Zins, Stephen R., Nelson, Christian D. S., Maginnis, Melissa S., Banerjee, Rahul, O'Hara, Bethany A., Atwood, Walter J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911681/
https://ncbi.nlm.nih.gov/pubmed/24198413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02766-13
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