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Neurovascular pericytes are susceptible to infection by JC polyomavirus

ABSTRACT Progressive multifocal leukoencephalopathy (PML), an often-fatal neurodegenerative disease, is caused by the neuroinvasive polyomavirus JCPyV. Peripheral organs, including the kidney, are the site of lifelong persistent infections that are asymptomatic. In a subset of immunosuppressed or im...

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Principais autores: Bethany A. O'Hara, Kaitlin Garabian, Wenqing Yuan, Walter J. Atwood, Sheila A. Haley
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-09-01
Serier:Journal of Virology
Fag:
host range
pericytes
blood brain barrier
progressive multifocal leukoencephalopathy
JCPyV
polyomavirus
Online adgang:https://journals.asm.org/doi/10.1128/jvi.00616-25
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