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Histone Deacetylase Classes I and II Regulate Kaposi's Sarcoma-Associated Herpesvirus Reactivation

In primary effusion lymphoma (PEL) cells infected with latent Kaposi's sarcoma-associated herpesvirus (KSHV), the promoter of the viral lytic switch gene, Rta, is organized into bivalent chromatin, similar to cellular developmental switch genes. Histone deacetylase (HDAC) inhibitors (HDACis) re...

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Detalhes bibliográficos
Main Authors: Shin, Hye Jin, DeCotiis, Jennifer, Giron, Mario, Palmeri, Diana, Lukac, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911646/
https://ncbi.nlm.nih.gov/pubmed/24227836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02665-13
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