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The Cellular Peptidyl-Prolyl cis/trans Isomerase Pin1 Regulates Reactivation of Kaposi's Sarcoma-Associated Herpesvirus from Latency

Kaposi's sarcoma-associated herpesvirus (KSHV) causes Kaposi's sarcoma and primary effusion lymphoma. KSHV-infected cells are predominantly latent, with a subset undergoing lytic reactivation. Rta is the essential lytic switch protein that reactivates virus by forming transactivation-compe...

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Detalhes bibliográficos
Main Authors: Guito, Jonathan, Gavina, Aileen, Palmeri, Diana, Lukac, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911720/
https://ncbi.nlm.nih.gov/pubmed/24173213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02877-13
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