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Convergence of Kaposi's Sarcoma-Associated Herpesvirus Reactivation with Epstein-Barr Virus Latency and Cellular Growth Mediated by the Notch Signaling Pathway in Coinfected Cells

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of primary effusion lymphoma (PEL). All PEL cell lines are infected with KSHV, and 70% are coinfected with Epstein-Barr virus (EBV). KSHV reactivation from latency requires promoter-specific transactivation by the KSHV Rta pr...

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Detalhes bibliográficos
Main Authors: Spadavecchia, Sophia, Gonzalez-Lopez, Olga, Carroll, Kyla Driscoll, Palmeri, Diana, Lukac, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950570/
https://ncbi.nlm.nih.gov/pubmed/20686042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00894-10
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