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A Cell-Biased Effect of Estrogen in Prion Infection
Prion disorders are associated with the accumulation of a misfolded form (PrP(Sc)) of the normal prion protein, PrP(C). Here, we show that estrogen acts as a regulator of the processes of both prion infection and prion maintenance. Estrogen was found to be cell biased in its effect; it protected cel...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911640/ https://ncbi.nlm.nih.gov/pubmed/24227845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02936-13 |
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