A Lytic Viral Long Noncoding RNA Modulates the Function of a Latent Protein

Latent Kaposi's sarcoma-associated herpesvirus (KSHV) episomes are coated with viral latency-associated nuclear antigen (LANA). In contrast, LANA rapidly disassociates from episomes during reactivation. Lytic KSHV expresses polyadenylated nuclear RNA (PAN RNA), a long noncoding RNA (lncRNA). We...

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Autores principales: Campbell, Mel, Kim, Kevin Y., Chang, Pei-Ching, Huerta, Steve, Shevchenko, Bogdan, Wang, Don-Hong, Izumiya, Chie, Kung, Hsing-Jien, Izumiya, Yoshihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911622/
https://ncbi.nlm.nih.gov/pubmed/24257619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03251-13
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