Novel H7N9 Influenza Virus Shows Low Infectious Dose, High Growth Rate, and Efficient Contact Transmission in the Guinea Pig Model

The zoonotic outbreak of H7N9 subtype avian influenza virus that occurred in eastern China in the spring of 2013 resulted in 135 confirmed human cases, 44 of which were lethal. Sequencing of the viral genome revealed a number of molecular signatures associated with virulence or transmission in mamma...

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Autori principali: Gabbard, Jon D., Dlugolenski, Daniel, Van Riel, Debby, Marshall, Nicolle, Galloway, Summer E., Howerth, Elizabeth W., Campbell, Patricia J., Jones, Cheryl, Johnson, Scott, Byrd-Leotis, Lauren, Steinhauer, David A., Kuiken, Thijs, Tompkins, S. Mark, Tripp, Ralph, Lowen, Anice C., Steel, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911619/
https://ncbi.nlm.nih.gov/pubmed/24227867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02959-13
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