Novel H7N9 Influenza Virus Shows Low Infectious Dose, High Growth Rate, and Efficient Contact Transmission in the Guinea Pig Model

The zoonotic outbreak of H7N9 subtype avian influenza virus that occurred in eastern China in the spring of 2013 resulted in 135 confirmed human cases, 44 of which were lethal. Sequencing of the viral genome revealed a number of molecular signatures associated with virulence or transmission in mamma...

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Detalhes bibliográficos
Main Authors: Gabbard, Jon D., Dlugolenski, Daniel, Van Riel, Debby, Marshall, Nicolle, Galloway, Summer E., Howerth, Elizabeth W., Campbell, Patricia J., Jones, Cheryl, Johnson, Scott, Byrd-Leotis, Lauren, Steinhauer, David A., Kuiken, Thijs, Tompkins, S. Mark, Tripp, Ralph, Lowen, Anice C., Steel, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911619/
https://ncbi.nlm.nih.gov/pubmed/24227867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02959-13
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