Protection Provided by a Herpes Simplex Virus 2 (HSV-2) Glycoprotein C and D Subunit Antigen Vaccine against Genital HSV-2 Infection in HSV-1-Seropositive Guinea Pigs

A prophylactic vaccine for genital herpes disease remains an elusive goal. We report the results of two studies performed collaboratively in different laboratories that assessed immunogenicity and vaccine efficacy in herpes simplex virus 1 (HSV-1)-seropositive guinea pigs immunized and subsequently...

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Main Authors: Awasthi, Sita, Balliet, John W., Flynn, Jessica A., Lubinski, John M., Shaw, Carolyn E., DiStefano, Daniel J., Cai, Michael, Brown, Martha, Smith, Judith F., Kowalski, Rose, Swoyer, Ryan, Galli, Jennifer, Copeland, Victoria, Rios, Sandra, Davidson, Robert C., Salnikova, Maya, Kingsley, Susan, Bryan, Janine, Casimiro, Danilo R., Friedman, Harvey M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911559/
https://ncbi.nlm.nih.gov/pubmed/24284325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03163-13
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