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Immunization with a Vaccine Combining Herpes Simplex Virus 2 (HSV-2) Glycoprotein C (gC) and gD Subunits Improves the Protection of Dorsal Root Ganglia in Mice and Reduces the Frequency of Recurrent Vaginal Shedding of HSV-2 DNA in Guinea Pigs Compared to Immunization with gD Alone
Attempts to develop a vaccine to prevent genital herpes simplex virus 2 (HSV-2) disease have been only marginally successful, suggesting that novel strategies are needed. Immunization with HSV-2 glycoprotein C (gC-2) and gD-2 was evaluated in mice and guinea pigs to determine whether adding gC-2 to...
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主要な著者: | , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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American Society for Microbiology
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187515/ https://ncbi.nlm.nih.gov/pubmed/21813597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00849-11 |
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