A p21-ZEB1 Complex Inhibits Epithelial-Mesenchymal Transition through the MicroRNA 183-96-182 Cluster

The tumor suppressor p21 acts as a cell cycle inhibitor and has also been shown to regulate gene expression by functioning as a transcription corepressor. Here, we identified p21-regulated microRNAs (miRNAs) by sequencing small RNAs from isogenic p21(+/+) and p21(−/−) cells. Three abundant miRNA clu...

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Detalhes bibliográficos
Main Authors: Li, Xiao Ling, Hara, Toshifumi, Choi, Youngeun, Subramanian, Murugan, Francis, Princy, Bilke, Sven, Walker, Robert L., Pineda, Marbin, Zhu, Yuelin, Yang, Yuan, Luo, Ji, Wakefield, Lalage M., Brabletz, Thomas, Park, Ben Ho, Sharma, Sudha, Chowdhury, Dipanjan, Meltzer, Paul S., Lal, Ashish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911499/
https://ncbi.nlm.nih.gov/pubmed/24277930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01043-13
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