Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

The microRNA-183/96/182 cluster is highly expressed in the retina and other sensory organs. To uncover its in vivo functions in the retina, we generated a knockout mouse model, designated “miR-183C(GT/GT),” using a gene-trap embryonic stem cell clone. We provide evidence that inactivation of the clu...

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Bibliografske podrobnosti
Main Authors: Lumayag, Stephen, Haldin, Caroline E., Corbett, Nicola J., Wahlin, Karl J., Cowan, Colleen, Turturro, Sanja, Larsen, Peter E., Kovacs, Beatrix, Witmer, P. Dane, Valle, David, Zack, Donald J., Nicholson, Daniel A., Xu, Shunbin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568372/
https://ncbi.nlm.nih.gov/pubmed/23341629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212655110
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