Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

The microRNA-183/96/182 cluster is highly expressed in the retina and other sensory organs. To uncover its in vivo functions in the retina, we generated a knockout mouse model, designated “miR-183C(GT/GT),” using a gene-trap embryonic stem cell clone. We provide evidence that inactivation of the clu...

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Bibliografiset tiedot
Päätekijät: Lumayag, Stephen, Haldin, Caroline E., Corbett, Nicola J., Wahlin, Karl J., Cowan, Colleen, Turturro, Sanja, Larsen, Peter E., Kovacs, Beatrix, Witmer, P. Dane, Valle, David, Zack, Donald J., Nicholson, Daniel A., Xu, Shunbin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
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PNAS Plus
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568372/
https://ncbi.nlm.nih.gov/pubmed/23341629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212655110
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