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Role of pncA and rpsA Gene Sequencing in Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from Southern China

We sequenced pncA and rpsA genes plus flanking regions of 161 Mycobacterium tuberculosis isolates and found 10 new pncA and 3 novel rpsA mutations in pyrazinamide-resistant strains determined by the Bactec MGIT 960 system. The 3′ end of rpsA might be added as the target of molecular detection of pyr...

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Xehetasun bibliografikoak
Egile Nagusiak: Tan, Yaoju, Hu, Zuqiong, Zhang, Tianyu, Cai, Xingshan, Kuang, Haobin, Liu, Yanwen, Chen, Junyu, Yang, Feng, Zhang, Ke, Tan, Shouyong, Zhao, Yanlin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911430/
https://ncbi.nlm.nih.gov/pubmed/24131688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01903-13
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