Hepatitis B virus integration in hepatocellular carcinoma DNA: duplication of cellular flanking sequences at the integration site.

The integrated form of hepatitis B virus (HBV) in the human hepatoma cell line huH2-2 and its cellular counterpart sequence have been cloned and analyzed. Blot hybridization analysis and nucleotide sequencing indicated that a single copy of the 1895-base-pair (bp) subgenomic region of HBV DNA, spann...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Yaginuma, K, Kobayashi, M, Yoshida, E, Koike, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1985
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391120/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2989822/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.13.4458
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